5/27/2012

Image Analysis in Histology (Postgraduate Medical Science) Review

Image Analysis in Histology (Postgraduate Medical Science)
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This is a good text covering the important and expanding area of image analysis. However, to get the best out of it, one would need to be studying a course on Image Analysis (such as the MSc. run by the Royal Postgraduate Medical School, London for whom the book is aimed), and using iamge analysis systems so as to put into practice the information detailed within the text.
The other main fault is that, to some extent, it demands a degree of knowledge of computer-based image systems as well as the reader knowing how to produce histological sections. Few students would have sufficient grounding in both areas to pick this book up and read it from cover to cover.
In summary, it is a good book for those studying image anlaysis (eg MSc.) and should be read in concert with lectures etc on this material, but it is not for general teaching use. If you are interested in this material, then you should first look at a copy from your library (or via inter-library loans service).

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This volume provides a timely and useful introduction to the theory and practical application of image analysis in histology. This powerful research technique can be used to detect not only stored products in a cell (immunocytochemistry) but the synthetic machinery and the genes that control it (in situhybridisation), as well as the specific binding sites that act as receptors for a molecule following its release (in vitroautoradiography). The book provides a good introduction for beginners before looking in greater detail at more advanced material in selected areas. The volume highlights the importance of technique in gathering quantitative information. The book is divided into four sections: introductory material, image acquisition, image processing, and applications. The applications areas include quantitative immunochemistry, quantification of nerves and neurotransmitters and automated grain counting in in situhybridisation histochemistry.

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