8/06/2012

It's Great Oops, No It Isn't: Why Clinical Research Can't Guarantee The Right Medical Answers Review

It's Great Oops, No It Isn't: Why Clinical Research Can't Guarantee The Right Medical Answers
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I read this book because I'm a mom who is really concerned about the medications I take and give to my kids. Too often, it seems like a "wonder drug" turns out to be a dud and has to be removed from the market. You read about a study in the newspaper one day, and then it is contradicted just a little while later. "It's Great" helped me understand why this happens. It describes challenges in clinical trials - and includes a section on statistics that is easy to follow. The book is really comprehensive, and it includes information about how politicians, the media and the government are involved in the process. It doesn't hold back on criticizing the FDA and the pharmaceutical industry, but it also supports the people who do research. I think it would be good for doctors to read this book, too, so they can better explain 'the studies' to their patients.

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This book dissects medical research methodology and through a penetrating inquiry into its triumphs and tragedies explains why correct answers are so hard to achieve. What emerges from this inquiry is the unexpected and stunning conclusion that medical researchers can never be sure that they've ended up with a truthful answer. In It's Great! readers learn why the quest for knowledge through clinical trials is fraught with problems that even the best researchers cannot overcome.A fascinating gallery of cases illustrates the perils investigators face. Particular emphasis is given to the 'clinical trial", the so-called gold standard for medical research, and its seven fatal flaws show succinctly why getting the right research answer is so problematic. In example after example, the author challenges the notion that medical research is too complex for the average citizen to comprehend. Understanding the imperfect world of clinical research allows the reader to step up and begin to ask his or her own questions, to challenge conclusions, to have doubts and not be afraid to raise them. People who care about their health and the health of others should not be innocent bystanders; they have a right, maybe even an obligation to become involved. After all, it's their health that is at stake.

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